I feel like outside of the usual ones (Spiderman, Batman, maybe Superman and the X-Men) capeshit is going to continue being in a rough period as far as the box office is concerned, which may lead to a lot of these eventually going direct to streaming. I can't imagine people flocking to theaters to watch "Thunderbolts" or whatever. I also think that for some audience members, there's been a feeling of "wait, this is still going on" post "Endgame", which-even with more being announced afterwards-felt like an endpoint. It wasn't, but continuing after that-plus all the TV shows and catching up, plus so many being made and coming up-then yeah, people are going to get exhausted and indifferent.
I'm not even saying "superhero fatigue" here (okay maybe I sort of am). I'm just saying that the golden era for this kind of movie seems to be over, and there's no going back to the massive success of the 2010s.