If anyone here likes Civilization series or 4X type games, I'd recommend Endless Legend. Game just came out recently and I've been immensely enjoying it since yesterday. The AI is a bit timid once you build up a decent army, but I like it. There are many different ways to win the game as well. Questing (I think?), Expansion, Commerce, Science, Diplomatic, Domination, and I think two or three others I'm forgetting.
It is a fantasy/sci-fi type of world, so if you want something realistic, this isn't your game. Also, it has a mechanic for winter in which you get hit by a lot of harsh conditions. When winter hits, you lose food production (like lots of it to all of it). I only so far have experience with the Vaulters, and they've got ways around it later since they are a Science faction, but early on, winter is your worst enemy.
Oh, and no mods just yet as it is really that new. For those wondering who made the game, it is Amplitude Studio that did.